近四分之一世紀，隨著生物化學和分子生物學學科的飛速發展，對普通醫學、遺傳學、免疫學、發育生物學和生物物理學的發展作出了重大貢獻。廣泛學科的研究人員越來越需要了解當前生物化學和分子生物學進展的重要性，而生物化學和分子生物學界的成員本身則尋求與各自專業無關的領域進展的簡明信息。生物化學和分子生物學的評論認為，寫得好的評論文章是整合和有意義地理解大量的，經常是矛盾的文獻的有效手段。綜述文章還通過綜合已知事實、富有成果的假設和新概念，為創造性的學術提供了機會。因此，生物化學和分子生物學的評論發表了高質量的評論，這些評論組織、評估和介紹了生物化學和分子生物學領域的高影響、當前問題的現狀。選題是根據杰出科學家咨詢委員會的建議進行的，該委員會還建議具有特殊能力的作者。所選主題足夠寬泛，能夠吸引廣大讀者，但重點足夠集中，能夠在單個作者的能力范圍內。作者的選擇是基于他們在該領域的活動和他們證明的能力，以產生一個良好的書面出版物。

As the discipline of biochemistry and molecular biology have greatly advanced in the last quarter century, significant contributions have been made towards the advancement of general medicine, genetics, immunology, developmental biology, and biophysics. Investigators in a wide range of disciplines increasingly require an appreciation of the significance of current biochemical and molecular biology advances while, members of the biochemical and molecular biology community itself seek concise information on advances in areas remote from their own specialties.Critical Reviews in Biochemistry and Molecular Biology believes that well-written review articles prove an effective device for the integration and meaningful comprehension of vast, often contradictory, literature. Review articles also provide an opportunity for creative scholarship by synthesizing known facts, fruitful hypotheses, and new concepts. Accordingly, Critical Reviews in Biochemistry and Molecular Biology publishes high-quality reviews that organize, evaluate, and present the current status of high-impact, current issues in the area of biochemistry and molecular biology.Topics are selected on the advice of an advisory board of outstanding scientists, who also suggest authors of special competence. The topics chosen are sufficiently broad to interest a wide audience of readers, yet focused enough to be within the competence of a single author. Authors are chosen based on their activity in the field and their proven ability to produce a well-written publication.