《生物醫學信息學雜志》(前身為《計算機與生物醫學研究》)已重新設計，以反映對生物醫學信息學領域高質量原創研究論文和評論的承諾。盡管發表的文章的動機是在生物醫學科學的應用(例如，臨床醫學、衛生保健、人口健康、成像和生物信息學)，該雜志強調新方法和技術的報告，具有普遍適用性，并形成了生物醫學信息學發展的基礎。關于醫療設備的文章和對已完成系統的正式評價，包括信息技術的臨床試驗，一般更適合在其他地點發表。如果系統描述能夠說明和證實作為報告主要焦點的基本方法，則系統描述是受歡迎的。

The Journal of Biomedical Informatics (formerly Computers and Biomedical Research) has been redesigned to reflect a commitment to high-quality original research papers and reviews in the area of biomedical informatics. Although published articles are motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, imaging, and bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices, and formal evaluations of completed systems, including clinical trials of information technologies, would generally be more suitable for publication in other venues. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report.